Acesys_brochure_2011

Acesys Pharmatech, Inc.

Acesys Pharmatech, founded in 2004 by veterans from Schering Plough and Merck in USA, specializes in chemical synthesis of building blocks, pharmaceutical intermediates and FTE based medicinal chemistry. Our services include Custom Synthesis, Library Design and Synthesis, FTE based (Exploratory) Medicinal Chemistry, Process Development and cGMP Manufacture (in USA and China). With main research labs and manufacturing plant in China and cGMP kilo labs in USA, Acesys combines USA quality and standard with highly affordable price to provide our customers best services. We also carry a variety of catalog products, mainly in heterocyclic and chiral compounds.

Library Synthesis (Swiss-Cheese Design with Lipinski-rule Screening):

 Solution Phase library design and synthesis

 Solid Phase Library: IRORI based library design & synthesis

Custom Synthesis:

 Patent compounds re-synthesis & Modification  Intermediate Scale-up: gram-kg scale

Medicinal Chemistry:

 Exploratory Medicinal Projects Initiation  Full Medicinal Chemistry

Global Distributors: France: Sigma Aldrich Chimie SARL

80 RUE DE LUZAIS – Z.I DE CHESNES

38297 SAINT QUENTIN FALLAVIER – France Tel : +33.(0) 4.74.82.28.73 Fax: +33(0).4.74.99.10.77 Email: fraoutsourcing@sial.com

Spain:

Cymit Quimica, S.L (www.cymitquimica.com)

Guillem Tell, 42-44, 08006 BARCELONA, Spain Tel: 93 241 29 27; Fax: 93 414 49 79 Email: info@cymitquimica.com

Japan: SHIGEMATSU & CO.,LTD (www.shigematsu-bio.com) Head Office : 2-5 Awaji-machi 2 Chome , Chuo-ku Osaka , 1-0047, Japan

Tel: 81-6-6231-6146; Fax: 81-6-6231-6149

Acesys Pharmatech

11 Industrial Rd, Fairfield, NJ, USA

USA Toll Free Tel: +1-800-792-0471, USA Toll Free Fax: +1-866-516-84 Email: info@acesysweb.com http:// www.acesysweb.com

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Selected Acesys Catalog Compounds 2011

1.1 Piperizine Series (>100 compounds):

HN$495/5g - $995/5g HNONBocOA1610SBocNONHOA1609SHNNBocA1615RBocNNHA1655RHNNBocA1618RBocNNHA1658RHNNBocA1604SBocNNHA1603SHNNBocA1613RBocNOHNHA1653RHNNBocA1616SBocNNHA1656SHNNBocA1619SBocNNHA1659SOHHNNBocA1604RBocNNHA1603RHNNBocA1613SBocNOHNHA1653SHNNBocA1616RBocNNHA1656RHNNBocA1619RBocNNHA1659ROHHNNCOOHBocA1607RBocNNCOOHHA1606RHNNBocA1614SBocNNHA16SHNNBocA1617SBocNNHA1657SOthers:HNNCOOHBocA1607SBocNNCOOHHA1606SHNNBocA1614RBocNNHA16RHNNBocA1617RBocNNHA1657RHNNRBocHNNRBocONBocOA1610RBocNONHOA1609RHNNBocA1615SBocNNHA1655SHNNBocA1618SBocNNHA1658SBocNNHRR=VariableBocNNHR

CBZ- and FMOC- protection also available!

Acesys Pharmatech

11 Industrial Rd, Fairfield, NJ, USA

USA Toll Free Tel: +1-800-792-0471, USA Toll Free Fax: +1-866-516-84 Email: info@acesysweb.com http:// www.acesysweb.com

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Selected Acesys Catalog Compounds 2011

1.2 Piperidine Series (>100 compounds):

NH2HNBocNH2NBocNHHNBocNBocNBocHNHNNBocNHA1309NH2A1310HNA1307NH2A1308HNBocA1401H2NA1452BocNHBocNBocNBocNHNHNBocNHA1305NH2(R)A1306NH2(S)A1303BocA1304BocA1301A1302HN(S)HN(R)H2N(R)H2N(S)NBocNBocNHNHNBocNBocA1303RBocNH(R)A1303SBocNHA1304SA1304RA1301RA1301SN(R)bocN(S)bocN(R)(S)NNbocNH(S)NHNNNbocA1302ROA1302SA1323RCNA1323SA1322RA1322SONBocNBocCNNBocNBocHNRHNNBocRA1305A1451A1494A1495NBoc

CBZ- and FMOC- protection also available!

Acesys Pharmatech

11 Industrial Rd, Fairfield, NJ, USA

USA Toll Free Tel: +1-800-792-0471, USA Toll Free Fax: +1-866-516-84 Email: info@acesysweb.com http:// www.acesysweb.com

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Selected Acesys Catalog Compounds 2011

1.3 Pyrollidine Series (>100 compounds):

BocNHNHA1201Boc(R)NH2NH2NBocA1202NBocA1203NH2NHA1204RNH2(S)NHBocNHA1204NHBocNH2NBocA1205NH2(R)HNBocNHA1206HNBoc(R)NH(R)NH2(R)(S)NHA1201RNBocA1202RNBocA1203RNBocA1205RNHBocNH2(S)NHA1206RBoc(S)(R)(S)HNBoc(S)NHNNH2NHA1201SBocA1202SNBocA1203SNHA1204SNBocA1205SNHA1206S

1.3A 2,4-di-substituted Pyrollidines (48 compounds): $595/g In stock

BocNHBocNHBocNHBocNHBocNH(R)(R)(R)(S)(S)(R)O(S)OH(R)(R)OH(R)OH(S)OH(S)ONNNNNNOOOOOHOHHHHHA1247A1532A1533A1535A1239A1245BocNHH2N(S)H2N(R)H2N(R)H2N(R)H2N(S)OH(R)OH(S)NOBocA1248H2N(R)(S)NOBocA1508H2NOH(S)OH(R)H2N(S)O(R)(R)NOBocA1509H2NH2N(R)NOBocA1240NOBocA1246H2N(S)ONOBocA1511H2NOH(R)(R)OH(S)OH(S)NBocA1244BocHNNBocA1506BocHNNBocA1507BocHN(S)OH(S)O(S)(R)NBocA1232NBocOA1236BocHNONBocOA1512Boc(R)(R)(S)OH(R)(R)OH(S)BocHN(R)HN(S)OH(S)(S)NHA1243

NHA1505NHA1504(S)OHO(S)NHA1231NHOA1235O

NHOA1534CBZ- and FMOC- protection also available!

Acesys Pharmatech

11 Industrial Rd, Fairfield, NJ, USA

USA Toll Free Tel: +1-800-792-0471, USA Toll Free Fax: +1-866-516-84 Email: info@acesysweb.com http:// www.acesysweb.com

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Selected Acesys Catalog Compounds 2011

1.4 Azetidine Series (>60 compounds):

H2NNBocHNNHBocHNHNBocBocNNH2A1101A1102A1103HNCbzA1104NNNONHONCNNNA1107ONBocHOA1106NBocA1144BocA1159NCHONBoc

A1110A1109A11081.5

H2NOther mono-protected di-amines:

HNBocH2NNHBocH2NBocHNNBocNHA1005H2NNBocA1006H2NNBocA1012H2NNBocA1601HNNBocA1007NHHNBocA1008NHNHBocHNA1011NHBocA1002H2NNHBoc

A1009HNA1010HNHNA1013A1001H2NBocH2NBocH2NBocH2NNHBocH2NNHBocA1031BocNHNH2A1033BocNHNH2BocA1035NHNH2BocA1038NHNH2BocA1040NHNH2

A1032A1034A1036A1037A1039

CBZ- and FMOC- protection also available!

Acesys Pharmatech

11 Industrial Rd, Fairfield, NJ, USA

USA Toll Free Tel: +1-800-792-0471, USA Toll Free Fax: +1-866-516-84 Email: info@acesysweb.com http:// www.acesysweb.com

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Selected Acesys Catalog Compounds 2011

1.6 Chiral Amines (>100 compounds): (> 20 compounds in stock)

NH2FA5011RNH2RCF3NH2NH2F3CNH2F3CNH2NH2A5040SNH2OHA5014RNH2ROA5142SNH2ROA5143SNH2ROCNA5010RRBothR&S

1.7 Substituted Indanones (>40 compounds):

CF3F3COA9039OHOOA9026A9027OOOHA9028OOF3CA9040ONH2FFFOOA9032CNFA9038A9002A9033OCOOHO2NA9025NCOA9029OA9030O

1.8 Special Amino Acid Series (>60 compounds):

H2NCOOHBocNHCOOHNHH2NCOOHBocNHCOOHNHH2NCOOHNNBocBocA4109H2NCOOHA4158H2NCOOHA41BocNHCOOHNHA4162H2NCOOHNBocA4163OHH2NR1R2OA4102

A4103A4139A4138

1.9 Substituted Indoles (>100 compounds):

FFNHFNHNO2NO2OOHNHNHNHA2175OOOHNHA2118OOONHA2148A2032A2143RRNHR=Me,NH2,Cl,F,NO2,OH,OMe,etcNHR=COOH,CHO,CN,CH3,CH2COOH,etc.A2183A2182

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Acesys Pharmatech

11 Industrial Rd, Fairfield, NJ, USA

USA Toll Free Tel: +1-800-792-0471, USA Toll Free Fax: +1-866-516-84 Email: info@acesysweb.com http:// www.acesysweb.com

Selected Acesys Catalog Compounds 2011

2.0 Reference Standards or APIs:

HOOHH2NHNH2NNHNOACS8044:EntecavirNNNHAcOHACS8080:eZetimibeCONH2NHOHOOHOHFONFACS8044:PeramivirOOHNONNCF3OHNOHOOCONNCOOHCF3ONSSONNACS8016HOOCCOOHACS8066ACS8066

OAcOAcONHAcOHNOOONHOOOOOOOPPOHOHHNONHHNOHNOOONOOOOHOOHO

OCOCF3OACS8093ONH2ACS8034HOOHHONONOHBONH2.HClFNOCOOHNSOONHNHHOHOOHACS8084ACS8057ACS8045

For more information, please visit our website at www.acesysweb.com. You can search our website by CAS, Catalog No, Name and sub-structure.

Acesys Pharmatech

11 Industrial Rd, Fairfield, NJ, USA

USA Toll Free Tel: +1-800-792-0471, USA Toll Free Fax: +1-866-516-84 Email: info@acesysweb.com http:// www.acesysweb.com

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